Figure 5From: Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinaseMale GSK3α.KO mice are infertile. A. Breeding performance of GSK3α.KO mice versus FvB mice, estimated as number of pups and number of litters over a period of 111 days from 5 breeding couples/genotype). B. Testis weight, sperm cell counting and motility index assessed in males (n=5). All data (mean±SEM) are statistically analyzed by unpaired Student’s t-test (two-tailed): Testis weight, * p=0.030; sperm cells, p=0.198; motility index, * p=0.032. The red symbols in panels A and B represent a sterile FvB male. C. Sperm cells from GSKα.KO and FvB wild-type mice. Inset: single sperm at higher magnification.Back to article page