Figure 6

Motor function and electrophysiological recovery after NS/PC transplantation. A, Hindlimb motor function was assessed weekly by BMS score. The sub-acute TP group exhibited significantly better functional recovery than the vehicle control group at 14 DPI and thereafter, whereas no significant difference was observed between the chronic TP group and the vehicle control group. Values are means ± SEM (n = 10). ^**P < 0.01. B, Treadmill gait analysis using the DigiGait system revealed a significantly longer stride in the sub-acute TP group than in the chronic TP group or either control group 42 days after cell transplantation or PBS injection. Values are means ± SEM (sub-acute TP n = 10, chronic TP and each control n = 8). ^**P < 0.01. C, The sub-acute TP group walked for a significantly longer time on the rotating rod than the chronic TP group or either control group 42 days after cell transplantation or PBS injection. Values are means ± SEM (n = 10). ^**P < 0.01. D, Representative profiles of MEP in the sub-acute TP, chronic TP, and both control groups 42 days after cell transplantation or PBS injection.