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Figure 6 | Molecular Brain

Figure 6

From: Interactions between αCaMKII and calmodulin in living cells: conformational changes arising from CaM -dependent and -independent relationships

Figure 6

Effects of mutations at T286/305/306 upon the molecular dynamics of αCaMKII in SH-SY5Y cells. Time lapse imaging of αCaMKII mutants. Graphs show relative YFP/CFP emission ratio (open circle, αCaMKII mutant fusion proteins; filled circle, WT αCaMKII fusion proteins). Black bar shows the period of ionomycin application. (A, B) T286A. (C, D) T286D. (E, F) T305/306A. (G, H) T286/305/306A. (A, C, E, G) Interaction of αCaMKII with CaM. (B, D, F, H) Conformational change of αCaMKII. 20–30 cells were analyzed in each group.

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Molecular Brain

ISSN: 1756-6606