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Figure 4 | Molecular Brain

Figure 4

From: CD38 in the nucleus accumbens and oxytocin are related to paternal behavior in mice

Figure 4

Effect of CD38 re-expression in the NAcc on sucrose preference in wild-type and knockout mice. (A) Sucrose uptake ratio (preference) by CD38+/+ (blue circles) and CD38−/− (yellow circles) young adult (non-parental) males at the indicated concentrations of sucrose over water in the two-bottle test over 24 hours. N = 20 each out of a total of 320 males. A Two-way ANOVA was used: wild-type mice (F5,124 = 12.97, P = 0.000), CD38−/− mice (F5,124 = 16.97, P = 0.0000) and their interaction with sucrose concentrations (F5,124 = 3.80, P = 0.0006) were found to be significant factors. A two-tailed Student t-test was used to test significance of the difference between CD38+/+ and CD38−/− mice at 1%, #P < 0.002. (B) Sucrose preference tested with 1% sucrose in CD38+/+ (blue) and CD38−/− mice treated with (green) or without (red) OT and CD38−/− mice expressing either GFP (yellow) or HCD38 (amber). N = 7 males in each group. A One-way ANOVA followed by Bonferroni’s post hoc test was performed: F4,88 =11.00, P = 0.0000. A two-tailed Student t-test was performed: #P = 0.000, **P < 0.05.

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