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Figure 1 | Molecular Brain

Figure 1

From: Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal netsin gamma-aminobutyric acidergic interneurons of the frontal cortex in adultmice

Figure 1

Decrease in the number of parvalbumin+ cells in the mFC.(A) Representative coronal images ofparvalbumin+ (magenta)/PNN+ (green) cells in the mFC of micetreated with vehicle (upper row) or FLX (lower row). Mice received FLXfor 3 weeks at 15 mg/kg/day. (B) Quantification of thenumber of parvalbumin+, PNN+, parvalbumin+/PNN+ cells, and theproportion of parvalbumin+/PNN+ cells in the total number ofparvalbumin+ cells (n = 4 mice each; 11-week-old).FLX, fluoxetine; PNN, perineuronal net; PV, parvalbumin.

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Molecular Brain

ISSN: 1756-6606