Skip to main content
Figure 2 | Molecular Brain

Figure 2

From: Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal netsin gamma-aminobutyric acidergic interneurons of the frontal cortex in adultmice

Figure 2

Expression of parvalbumin and PNN in the hippocampal CA3 and RTN. (A,C) Double-staining for parvalbumin (magenta) and PNN (green) incoronal sections of the hippocampal CA3 region (A) and RTN(C). Mice received FLX for 3 weeks at 15 mg/kg/day.(B, D) The number of parvalbumin+, PNN+,parvalbumin+/PNN+ cells, and the proportion ofparvalbumin+/PNN+ cells in the total number ofparvalbumin+ cells were quantified in the hippocampal CA3 region(B) and RTN (D) (n = 4 mice each;11-week-old). Note that a decreased number of parvalbumin+ cellswere found in the hippocampal CA3, but not in the RTN. CA, cornuammonis; FLX, fluoxetine; PNN, perineuronal net; PV, parvalbumin; RTN,reticular thalamic nucleus.

Back to article page

Molecular Brain

ISSN: 1756-6606