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Table 2 Monitored ion transitions and their parameter settings of mass spectrometer for the detection and measurements of Ro0711401

From: Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1

Precursor ion

Fragment

DP

EP

CE

CXP

( m/z, amu)

( m/z, amu)

(V)

(V)

(V)

(V)

RO (361.0)

181.1

47.0

5.8

25.0

2.9

 

153.0

47.0

5.8

19.1

2.8

IS (351.2)

234.0

42.0

7.0

23.7

3.2

 

170.0

42.0

7.0

26

2.6

  1. DP – Declustering Potential; EP – Entrance Potential; CE – Collision Energy; CXP – Collision Cell Exit Potential.