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Table 2 Monitored ion transitions and their parameter settings of mass spectrometer for the detection and measurements of Ro0711401

From: Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1

Precursor ion Fragment DP EP CE CXP
( m/z, amu) ( m/z, amu) (V) (V) (V) (V)
RO (361.0) 181.1 47.0 5.8 25.0 2.9
  153.0 47.0 5.8 19.1 2.8
IS (351.2) 234.0 42.0 7.0 23.7 3.2
  170.0 42.0 7.0 26 2.6
  1. DP – Declustering Potential; EP – Entrance Potential; CE – Collision Energy; CXP – Collision Cell Exit Potential.