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Table 2 qRT-PCR analysis of genes using the frontal cortex (the same genes in Table  1 )

From: Involvement of the N-methyl-d-aspartate receptor GluN2D subunit in phencyclidine-induced motor impairment, gene expression, and increased Fos immunoreactivity

Symbol

Definition

n

KOS/WS (vs. WS) %

WPCP/WS (vs. WS) %

KOPCP/KOS %

(vs. WPCP/WS)

Significantly changed gene expressions induced by PCP of wild-type mice

Fos

FBJ osteosarcoma oncogene

4

89 ± 7

271 ± 16 **

179 ± 5

c

Fosb

FBJ osteosarcoma oncogene B (Fosb)

3

98 ± 7

246 ± 69 **

134 ± 19

a

Ddit4

DNA-damage-inducible transcript 4 (REDD1)

3

112 ± 5

200 ± 8 **

164 ± 4

b

Egr4

early growth response 4

4

107 ± 19

164 ± 56 **

86 ± 3

b

Tsc22d3

TSC22 domain family, member 3, transcript variant 1 (DSIPI)

4

100 ± 7

209 ± 24 *

190 ± 15

a

Gadd45g

growth arrest and DNA-damage-inducible 45 γ

4

103 ± 2

189 ± 25 *

146 ± 7

a

Cfp

complement factor properdin (Properdine)

4

105 ± 19

151 ± 9 **

126 ± 20

a

Slc2a1

solute carrier family 2 (GLUT1)

4

93 ± 5

149 ± 8 **

150 ± 5

a

Txnip

thioredoxin interacting protein, transcript variant 1

4

106 ± 8

143 ± 16 **

126 ± 10

a

Bag-3

Bcl2-associated athanogene 3

4

91 ± 6

142 ± 6 **

128 ± 6

a

Pglyrp1

peptidoglycan recognition protein 1 (PGRP-S)

3

93 ± 5

139 ± 12 **

128 ± 12

a

Arrdc

arrestin domain containing 3 (mKIAA1376)

3

110 ± 1

136 ± 14 *

115 ± 14

a

Rgc32

RIKEN cDNA 1190002H23 gene

4

97 ± 6

131 ± 7 *

123 ± 6

a

Significantly changed gene expressions induced by PCP of NR2D KO mice

Egr1

early growth response 1(zif-268)

4

94 ± 8

87 ± 8

67 ± 3

a

  1. Data are expressed as the mean percentage ± SEM relative to the saline treated controls.
  2. Compared to WS controls; *, p <0.05. **, p <0.01.
  3. Compared to WS controls; *, p <0.05. **, p <0.01. WPCP vs. KOPCP; a, not significant. b, p <0.05. c, p <0.01.