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Figure 4 | Molecular Brain

Figure 4

From: Analysis of sleep disorders under pain using an optogenetic tool: possible involvement of the activation of dorsal raphe nucleus-serotonergic neurons

Figure 4

Change in the dialysate levels of 5-HT induced by electrical stimulation in the mouse DRN at 7 days after sciatic nerve ligation. To investigate the effect of electrical stimulation of the DRN, we evaluated the dialysate 5-HT levels in the PFC in mice by in vivo microdialysis. The mice were subjected to electrical stimulation, sine-wave pulses (100 Hz, 150 μA), for 15 min. The data are expressed as percentages of the corresponding baseline levels ± SEM (n = 4). **p < 0.01 vs. sham. The X-axis shows different time points after stimulation.

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Molecular Brain

ISSN: 1756-6606