From: Rewiring of regenerated axons by combining treadmill training with semaphorin3A inhibition
Enzymes | IC50 (μm) |
---|---|
Semaphorin | 0.1-0.2 |
Matrix Metalloproteinase-1 (MMP-1) | >10 |
Matrix Metalloproteinase-7 (MMP-7) | 10 |
Matrix Metalloproteinase-2 (MMP-2) | >10 |
Matrix Metalloproteinase-3 (MMP-3) | >10 |
Matrix Metalloproteinase-9 (MMP-9) | >10 |
Phospholipase PLA2-1 | >10 |
Phospholipase PLC | >10 |
Caspase 1 | >10 |
Caspase 3 | >10 |
Caspase 6 | >10 |
Caspase 7 | >10 |
Caspase 8 | >10 |
Protein Tyrosine Phosphatase, CD45 | >10 |
Protein Tyrosine Phosphatase, PTP1B | >10 |
Protein Tyrosine Phosphatase, PTP1C | >10 |
Protein Tyrosine Phosphatase, T-Cell | >10 |
Sphingomyelinase, Neutral (N-SMase) | >10 |
Chemokine CCR1 | >10 |
Chemokine CCR2B | >10 |
Chemokine CCR4 | >10 |
Chemokine CCR5 | >10 |
Chemokine CXCR2 (IL-8B) | >10 |
Glucocorticoid | >10 |
Interleukin IL-1 | >10 |
Interleukin IL-2 | >10 |
Interleukin IL-6 | >10 |
Tumor Necrosis Factor (TNF), Non-selective | >10 |
Adhesion, fibronectin-mediated | >10 |
Adhesion, ICAM-1-Mediated | >10 |
Adhesion, VCAM-1-Mediated | >10 |
Cell proliferation, B-Cell+LPS | >10 |
Cell proliferation, T-Cell+Con A | >10 |
Mediator release, IL-1beta | >10 |
Mediator release, IFN-gamma | >10 |
Mediator release, IL-10 | >10 |
Mediator release, IL-2 | >10 |
Mediator release, IL-4 | >10 |
Mediator release, IL-5 | >10 |
Mediator release, IL-6 | >10 |
Mediator release, TNF-alfa, PBML | >10 |
Transcription response, NF-AT | >10 |
Transcription response, NF-kB | >10 |