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Figure 1 | Molecular Brain

Figure 1

From: Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia

Figure 1

Increased locomotor activity in open field test in Apc1638T/1638Tmice. (A) Distances traveled (genotype effect, F1,41 = 22.58, p < 0.0001; genotype × time interaction, F23,943 = 2.909, p < 0.0001), (B) time spent in the center of the compartment (genotype effect, F1,41 = 18.699, p < 0.0001; genotype × time interaction, F23,943 = 1.664, p = 0.0258), (C) counts of stereotypic behavior (genotype effect, F1,41 = 41.58, p < 0.0001; genotype × time interaction, F23,943 = 5.233, p < 0.0001), and (D) counts of vertical activity were recorded. The p values in the figure indicate genotype effect in two-way repeated measures ANOVA. Error bars indicate SEM.

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