Figure 6
Altered synapse morphology in Apc1638T/1638Tmice. (A) Golgi impregnated dendrites in the stratum oriens of the hippocampal CA1 region. The scale bar represents 2 μm. (B-E) Quantification of dendritic spine: (B) density, (C) length, (D) width, and (E) area. (F) Representative electron photomicrographs of hippocampal synapses. The PSD is visible as an electron-dense layer adjacent to the postsynaptic membrane. The scale bar represents 0.1 μm. (G-I) Quantification of PSD: (G) length, (H) thickness, and (I) area. Two-tailed Student’s t-test was used for statistical analysis.