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Figure 7 | Molecular Brain

Figure 7

From: Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia

Figure 7

Altered excitatory synaptic transmission in the hippocampal CA1 region of Apc1638T/1638Tmice. (A) Input–output relationship and (B) paired-pulse facilitation. (C) Long-term potentiation induced in standard saline. Tetanic stimulation was applied at 0 min. Scale bars, 10 ms, 0.5 mV. (D) Post-tetanic potentiation in the presence of D-APV. The number of slices used is indicated by “n”. Two-tailed Student’s t-test was used for statistical analysis.

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