Figure 3

The axon possesses the maximal ability of firing spikes in response to fluctuated signals, and the soma has the maximal ability of firing spikes in response to long-time steady depolarization. A) An example shows spike waveforms from the soma to different axonal segments. B) shows the input–output curves for the soma (red symbols) and different axonal fragments in 5 ~ 29 μm (light-reds), 30 ~ 55 μm (pinks) and >55 μm (blues) away from the soma, in which sequential spikes are induced by long-time steady depolarization. C) illustrates the maximal values of input–output curves (normalized stimuli at 10) for steady-state pulses versus distances of axonal bleb to the soma. D) A sample shows spike waveforms from the soma to different axonal segments. E) shows input–output curves for the soma (red symbols) and distinct axonal fragments in 5 ~ 29 μm (light-reds), 30 ~ 55 μm (pinks) and >55 μm (blues) away from the soma, in which the spikes are induced by the fluctuated depolarization (cosine wave at 50 Hz). F) shows the maximal values of input–output curves for the fluctuated pulses vs. distances of axonal bleb to the soma.