Skip to main content
Figure 3 | Molecular Brain

Figure 3

From: No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex

Figure 3

SB366791 cannot block the induction of LTP in the adult mice ACC. (A) Grouped data from 6 slices of 6 mice for SB366791 (20 μM), showing the normal induction of LTP in the superficial layer. (B) Summarized data in the deep layer (n = 6 slices/6 mice). Sample fEPSP recordings taken at the times indicated by the corresponding numbers are shown at the top of each plot. Arrows in (A and B) show the starting point of TBS application. Horizontal bars denote the period of drug delivery. Calibration: 100 μV, 10 ms. Error bars represent SEM. (C and D) Spatial analysis of the effect of SB366791 on LTP distribution in the ACC. Shown are polygonal graphs of the channels that were activated (blue, C) and that exhibited LTP (red, D) when TBS was delivered in the presence of SB366791 (n = 6 slices/6 mice). Vertical lines denote the specific layers in the ACC slice. SB366791 has no effect on the LTP distribution map in the ACC.

Back to article page