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Figure 6 | Molecular Brain

Figure 6

From: No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex

Figure 6

SB366791 cannot block the induction of LTD in the adult mice ACC. (A) Grouped data from 6 slices of 6 mice for SB366791 (20 μM), showing the normal induction of LTD in the superficial layer. (B) Summarized data in the deep layer (n = 6 slices/6 mice). Sample fEPSP recordings taken at the times indicated by the corresponding numbers are shown at the top of each plot. Horizontal bars denote the period of LFS or drug application as indicated. Calibration: 100 μV, 10 ms. Error bars represent SEM. (C and D) Spatial analysis of the effect of SB366791 on LTD distribution in the ACC. Shown are polygonal graphs of the channels that were activated (blue, C) and that exhibited LTD (red, D) when LFS was delivered in the presence of SB366791 (n = 6 slices/6 mice). Vertical lines denote the specific layers in the ACC slice. SB366791 has no effect on the LTD distribution map in the ACC.

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Molecular Brain

ISSN: 1756-6606