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Table 1 Effect of GABA on the properties of action potential in lateral amygdala from different groups of mice

From: Chronic stress impairs GABAergic control of amygdala through suppressing the tonic GABAA receptor currents

AP parameters

Control (n = 8)

p

CIS (n = 8)

p

CIS + metyrapone (n = 7)

p

ACSF

GABA

ASCF

GABA

ASCF

GABA

AP threshold (mV)

-36.29±1.28

-38.43±0.74

0.367

-40.74±2.09

-40.50±2.14

0.801

-38.97±1.21

-38.28±1.14

0.635

AP amplitude (mV)

80.25±2.41

81.45±2.50

0.597

78.83±2.05

79.57±1.51

0.595

82.73±1.45

80.60±2.98

0.386

Half AP width (ms)

2.09±0.12

2.10±0.09

0.900

2.12±0.14

2.14±0.11

0.817

2.01±0.15

2.04±0.10

0.548

  1. AP: action potential. ACSF: artificial cerebrospinal fluid. The number in parenthesis represents the number of neurons. p values were obtained from comparisons before and after GABA application using paired t test.
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Molecular Brain

ISSN: 1756-6606