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Figure 3 | Molecular Brain

Figure 3

From: Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus

Figure 3

Levels of hippocampal phosphorylated extracellular signal-regulated kinase 1/2 and phosphorylated p38 in the aCSF- and LPS-infused rats. (A) Representative western blot of extracellular signal-regulated kinase 1/2 (Erk1/2), phosphorylated Erk1/2 (p-Erk1/2), and actin. (B) Levels of p-Erk1/2 were higher in the hippocampi of the LPS-infused rats than in that of the aCSF-infused rats. (C) Representative western blot of p38, phosphorylated p38 (p-p38), and actin. (D) Levels of p-p38 were higher in the hippocampi of LPS-infused rats than in that of the aCSF-infused rats. *, p < 0.05. The relative expression levels of all proteins were determined by densitometry and normalized to actin.

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Molecular Brain

ISSN: 1756-6606