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Figure 5 | Molecular Brain

Figure 5

From: Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus

Figure 5

Confocal photomicrographs of dual staining for p-p38 and markers of cellular location in the CA1, CA3, and DG of the aCSF- and LPS-infused rats. Photomicrographs showed an overlap between p-p38-positive signals and NeuN, a neuronal marker (A), or CD11b, a microglial marker (B), or GFAP, an astrocyte marker (C). The p-p38-positive cells were observed mostly in neurons and also in glial cells. Compared with the aCSF-infused rats, levels of p-p38 expressing in the CD11b-positive microglia were increased only in the hippocampal CA3 region of the LPS-infused (D; *, p < 0.05) and levels of p-p38 expressing in the GFAP-positive astrocyte were significantly increased only in the hippocampal CA1 region of the LPS-infused rats (E; *, p < 0.01).

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Molecular Brain

ISSN: 1756-6606