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Figure 3 | Molecular Brain

Figure 3

From: Effect of the Brugada syndrome mutation A39V on calmodulin regulation of Cav1.2 channels

Figure 3

The Brugada mutation A39V does not alter N-terminal binding to CaM. A) CaM sepharose pull-down experiments of N1-EX, A39V-N1-EX and N1 GFP fusion proteins in 0.5 mM Ca2+, or 5 mM EGTA (B) run on SDS-PAGE with corresponding lysates (C) and blotted for GFP. Black lines mark where the gel picture was cut and irrelevant samples removed. These experiments were performed twice each.

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