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Figure 11 | Molecular Brain

Figure 11

From: Voltage-independent sodium channels emerge for an expression of activity-induced spontaneous spikes in GABAergic neurons

Figure 11

A diagram shows the conversion of silent voltage-independent sodium channel into active one in the axon of a GABAergic neuron after AISS expression. A) illustrates the functional silence of voltage-independent sodium channels (gray) on the axon, whereas VGSCs (blue) are active for the generation of the evoked spikes. B) illustrates the active state of this voltage-independent sodium channels on the axon (red), which are responsible for generating the spikelets or early phase of full spikes in AISS. VGSCs (blue) are activated for late phase of full spikes in AISS.

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