Figure 1
From: Extrasynaptic GABAA receptors in mediodorsal thalamic nucleus modulate fear extinction learning
Gabazine injection into the MD facilitates fear extinction. (A) experiment scheme. (B) Injection target. (C) Injection of gabazine (30 μM) into the MD (empty circles, n = 12) 30 min before extinction decreased freezing levels in both extinction learning, and the recall test in the next day compared with the mice that received vehicle injection into the MD (filled circles, n = 11), ↑, injection time point. (D) Normalized within-session extinction to percentage of the initial freezing levels of each group shows group difference and group x trial interaction in extinction rate. (E and F) No difference between these two groups in the locomotion, or anxiety. Data are means ± SEM.