Skip to main content

Table 1 G-protein isoforms

From: How much do we know about the coupling of G-proteins to serotonin receptors?

Protein name

Gene name

Validated at protein level

Validated at transcript level

G alpha proteins

Gαi1

GNAI1

2

-

Gαi2

GNAI2

4

6

Gαi3

GNAI3

1

-

Gα11

GNA11

1

-

Gα12

GNA12

1

5

Gα13

GNA13

1

2

Gα14

GNA14

-

1

Gα15 (or Gα16)

GNA15

1

2

Gαolf

GNAL

3

1

Gαo

GNAO

2

1

Gαq

GNAQ

1

2

Gαs

GNAS

7

4

Gαt1

GNAT1

1

-

Gαt2

GNAT2

1

-

Gαt3

GNAT3

-

1

Gαz

GNAZ

-

2

G beta proteins

Gβ1

GNB1

1

2

Gβ1-like

GNB1L

1

1

Gβ2

GNB2

1

2

Gβ2-like

GNB2L1

1

17

Gβ3

GNB3

1

3

Gβ4

GNB4

1

1

Gβ5

GNB5

3

3

G gamma proteins

Gγ1

GNGT1

-

2

Gγ2

GNG2

1

5

Gγ3

GNG3

-

1

Gγ4

GNG4

1

-

Gγ5

GNG5

1

-

Gγ7

GNG7

1

1

Gγ8

GNG8 (alias GNG9)

-

1

Gγ10

GNG10

1

-

Gγ11

GNG11

1

-

Gγ12

GNG12

1

-

Gγ13

GNG13

-

1

Gγt2

GNGT2 (alias GNG8 or GNG9)

-

2

  1. For each human G-protein, it is shown the number of the related isoforms subdivided by the validation status, according to UniProt. Note that, GNA15 is the homolog gene encoding the murine Gα15 and the human Gα16 [[13]].