Ultrastructure of hippocampus after acute LPS-induced inflammation. TEM hippocampal images of 0.9% NaCl-injected mice (A and B) and 10mg/kg LPS-treated mice (2 injections per 24 h, images C and D). No alteration of tissue integrity was observed in low magnification images (A and C). Images b and d represent magnified region of interest of white square in a and c, respectively. In these magnified images, mitochondria appeared with intact cristae (mt), endoplasmic reticulum (ER) was present with ribosomes, myelin rounded axons marked with white arrow and lysosomes (L) were observed. Five sections in each area (cortex and hippocampus) were observed for each mouse brain.