Figure 3
From: A mouse line for inducible and reversible silencing of specific neurons
IVMR expression in Rosa26-IVMR mice crossed with 3 Cre lines. (a-d) GFP immunostaining and IVMR in situ hybridization in the hippocampus (a, c) and cerebral cortex (b, d) of Rosa26-IVMR;CamKII-Cre mice. (e, f) Expression of IVMR mRNA in the hippocampus (e) and cerebral cortex (f) of Rosa26-IVMR;Emx1-Cre mice. (g, h) Expression of IVMR mRNA in the spinal dorsal horn (g) and dorsal root ganglion (h) of tamoxifen-treated Rosa26-IVMR;Prrxl1-CreER mice. CA1, CA1 region of the hippocampus; df, dorsal fasciculus; DG, dentate gyrus; DH, dorsal horn; lf, lateral fasciculus; I-VI, cortical layers. Scale bars, 200 μm in (f) applies to (a-e), 150 μm in (g) and 100μm in (h).