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Figure 6 | Molecular Brain

Figure 6

From: Sensitization of neurons in the central nucleus of the amygdala via the decreased GABAergic inhibition contributes to the development of neuropathic pain-related anxiety-like behaviors in rats

Figure 6

Increase in both percentage of adapting firing neurons and frequency of no adapting firing neurons in CeA nucleus in SNL-induced anxiety rats. (A): percentage of adapting (red color) and no adapting (blue color) firing neurons. Note that the percentage of adapting firing neurons is significantly increased in SNL rats compared to na''ve and sham rats. (B): frequency of no adapting firing neurons. Note that the frequency of action potentials in no adapting firing neurons is prominently increased in SNL rats compared to na''ve and sham rats. *p < 0.05, ***p < 0.001, one-way ANOVA, n = 7 na''ve, 11 sham and 11 SNL. (C): representative of evoked discharges of CeA neurons obtained from na''ve, sham and SNL rats, respectively. Action potentials are evoked by a depolarizing current of 600 ms, 300 pA. Note that adapting firing pattern is shown in SNL rat, while no adapting firing pattern exhibits in na''ve and sham rats. All recorded cells in each group are obtained from animals of na''ve (3 rats); sham (5 rats) and SNL (6 rats), respectively.

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Molecular Brain

ISSN: 1756-6606