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Figure 4 | Molecular Brain

Figure 4

From: Cortical parvalbumin and somatostatin GABA neurons express distinct endogenous modulators of nicotinic acetylcholine receptors

Figure 4

Lypd6 is expressed in a unique subpopulation of somatostatin interneurons. A) Representative images from double in situ hybridization of coronal sections of primary visual cortex labeled with probes directed against Lypd6 (green) and molecular markers of somatostatin subtypes neuropeptide Y or calbindin (red). B) Quantification of the percentage of total Lypd6+ neurons that co-express either neuropeptide Y or calbindin. C) Quantification of the percentage of each SST subtype marker (NPY or CB) that co-express Lypd6. D) Schematic representation of viral labeling of long-range SST neurons. E) Representative image of DISH for GFP and Lypd6 mRNA in V1 of SST-cre mice injected with retrograde cre-dependent GFP in S1. Arrowhead shows double labeled long-range SST neuron. Inset represents high-magnification (63 ) image of double labeling. Low and high magnification = 100 μm and 15 μm respectively.

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