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Figure 4 | Molecular Brain

Figure 4

From: Postsynaptic insertion of AMPA receptor onto cortical pyramidal neurons in the anterior cingulate cortex after peripheral nerve injury

Figure 4

NASPM had a long term inhibition on the LTP of ACC layer V neurons. (A) Samples and averaged results showing that bath application of NASPM (50'µM) for 30'min reduced the slope of fEPSP from layer V neurons in mice with nerve injury but not in mice with sham surgery. (B) Samples and averaged results showing that TBS induced stable long term potentiation of the fEPSP of layer V neurons. However, bath application of CP-AMPAR antagonist NASPM for 30'min reversed the LTP effect.

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