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Figure 2 | Molecular Brain

Figure 2

From: Effects of PI3Kβ overexpression in the hippocampus on synaptic plasticity and spatial learning

Figure 2

Impaired induction of p38 MAPK phosphorylation by chemical LTD in p110β-overexpressed hippocampal CA1 region. (A) Representative phospho/total p38 MAPK western blot from tdTomato- or p110β-overexpressed slices after chemical LTD induction (NMDA treatment). (B) Normalized basal phosphorylation level of p38 MAPK from tdTomato- or p110β-overexpressed slices. (C) Normalized phosphorylation level of p38 MAPK from tdTomato-overexpressed slices after chemical LTD induction (n = 5, p <0.05, paired Student s t-test). (D) Normalized phosphorylation level of p38 MAPK from p110β-overexpressed slices, after chemical LTD induction (n = 5, NS, paired Student s t-test).

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