Figure 1From: Lack of evidence of the interaction of the Aβ peptide with the Wnt signaling cascade in Drosophila models of Alzheimer's diseaseExpression of Aβ42 in the nervous system dramatically reduces the life span. (A-B) Survival curves of the indicated genotypes expressed either with the pan-neuronal driver elav-Gal4 (A) or the driver D42-Gal4 which expresses in the glutamatergic motoneurons (B). P < 0.0001 comparing the controls elav-Gal4 and D42-Gal4 to Aβ42 expression, respectively. p = 0.0028 comparing Aβ42; D42-Gal4 and Aβ42/OK371-Gal4; D42-Gal4. Co-expression of Fz2 or RNAi-Sgg did not rescue life span. P-values are calculated with the Log-rank test.Back to article page