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Table 1 Concentrations of cerebral metabolites (mmol/kg wet tissue weight) in the hippocampus, occipital cortex and cerebellum of control 0.5 hr rats measured by ex vivo 1 H NMR spectroscopy

From: Ex vivo 1H nuclear magnetic resonance spectroscopy reveals systematic alterations in cerebral metabolites as the key pathogenetic mechanism of bilirubin encephalopathy

Metabolites

Integral (ppm)

Hippocampus

Occipital cortex

Cerebellum

Lac

δ1.31-1.34

7.73 ± 0.95

9.70 ± 2.18

5.37 ± 0.74

Suc

δ2.39-2.41

5.53 ± 0.51

7.73 ± 0.79

5.50 ± 0.24

Ala

δ1.46-1.49

1.39 ± 0.16

1.91 ± 0.30

1.09 ± 0.12

Glu

δ2.33-2.38

8.75 ± 0.71

11.89 ± 1.53

5.76 ± 0.42

GABA

δ2.27-2.31

3.30 ± 0.23

3.97 ± 0.55

1.96 ± 0.17

Gly

δ3.54-3.56

1.13 ± 0.09

1.54 ± 0.13

0.80 ± 0.14

Asp

δ2.80-2.82

1.95 ± 0.20

3.08 ± 0.21

1.30 ± 0.15

Gln

δ2.45-2.50

1.01 ± 0.08

1.37 ± 0.10

0.72 ± 0.13

NAA

δ2.01-2.02

3.24 ± 0.23

4.65 ± 0.53

2.05 ± 0.15

mI

δ3.60-3.64

4.65 ± 0.26

6.82 ± 0.84

5.17 ± 0.26

Tau

δ3.40-3.44

14.29 ± 1.11

21.84 ± 2.27

8.55 ± 0.49