Comparative GluN2B degradation between brain areas. A. Representative immunoblot of GluN2B for 13 different cortical regions from brain SD025/13 (Additional file 1). These cortical regions included the Broadmann Areas (BA) 4, 11/12, 17, 19, 20/21, 37, 38, 39, 41/42 and 44/45 (Broca’s area), as well as three frontal cortex samples: frontal convexity (FC), anterior frontal convexity (Ant FC) and anterior frontal parasagital (Ant FPS). GluN2B degradation bands are indicated. B. Representative immunoblot of GluN2B for 5 limbic areas: Broadmann areas (BA) 23 and 24, anterior and posterior Hipocampus (HC) and amygdala (Amyg); and 8 sub-cortical regions: Pons, Midbrain (MB), Caudate nucleus (Caud nuc), Thalamus (Thal), Medulla (Med), Vermis, Basal ganglia mammillary body (BG mam) and Cerebellum (CB). GluN2B degradation bands are indicated. C. Plot summarizing HUSPIR values for 26 brain areas (13 cortical, 5 limbic and 8 sub-cortical) analysed by immunoblot for GluN2B degradation in 4 different brains (SD025/13, SD042/13, SD032/13 and SD023/13). HUSPIR values above one are indicated in green and below in red. Grey indicates no measure could be taken.