Figure 3

Comparison of tremor-related activity between two essential tremor models. (A) ERPs (top) and right forelimb (RF) EMG activity (bottom) upon α1^−/−;α1G^−/− tremor discharge (left), α1^−/−;α1G^−/− non-tremor discharge (center), and harmaline tremor discharge (right). Arrows indicate each tremor discharge. Spectrogram (B) and inter-trial coherence (C) for the EEG channel on the left S1. For A to C, 100 events were randomly chosen from among all events for comparisons between ERPs. (D) 10–30 Hz power (left) and inter-trial coherence (right) for the EEG channel on the left S1 (n = 3 for each). Asterisks indicate comparisons between α1^−/−;α1G^−/− tremor and harmaline tremor (light blue), and between tremor and non-tremor in α1^-/-;α1G^−/− mice (gray). *P < 0.05 (two-tailed t-test).