Table 1 Total numbers and groups of Sprague–Dawley rats used in this study
| Â | aLA group | Control group | HNMPA group | Sham group |
|---|---|---|---|---|
Age (wk) | 8.0 ± 0.3 | 8.0 ± 0.3 | 8.0 ± 0.3 | 8.0 ± 0.3 |
Body weight (g) | 270.9 ± 8.3 | 271.3 ± 8.1 | 270.8 ± 6.1 | 271.1 ± 7.5 |
No. of animals used for main experiment | 71 | 71 | 49 | 10 |
Micro-PET image/TTC stain | 1/30 (10 rats/day) | 1/30 (10 rats/day) | 0/30 (10 rats/day) | 0/3 (1 rat/day) |
Behavior test | 20 | 20 | 10 | 10 |
Micro-PET image/IHC & RT-PCR | 1/9 (3 rats/day) | 1/9 (3 rats/day) | 0/9 (3 rats/day) | 0/3 (1 rat/day) |
Immunofluorescence | 12 (4 rats/day) | 12 (4 rats/day) | 0 | 0 |
Mortality, % | 29.6 | 53.5 | 46.9 | 0 |