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Figure 2 | Molecular Brain

Figure 2

From: Dexmedetomidine inhibits Tetrodotoxin-resistant Nav1.8 sodium channel activity through Gi/o-dependent pathway in rat dorsal root ganglion neurons

Figure 2

DEX dose-dependently inhibits Na v 1.8 currents. (A, B) Typical traces illustrating the Nav1.8 currents in small-diameter DRG neurons recorded pre- (control) and post- (DEX) perfusion of DEX and wash out. (C) Dose-effect curve of DEX-induced inhibition of Nav1.8 currents. The currents were measured after a 1-min application of different concentrations of DEX.

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Molecular Brain

ISSN: 1756-6606