Figure 1From: A combination Alzheimer’s therapy targeting BACE1 and neprilysin in 5XFAD transgenic mice Western blot analysis of transgenic overexpression of neprilysin in 5XFAD mice. Equivalent levels of neprilysin are overexpressed in NEP · 5XFAD and BACE1+/− · NEP · 5XFAD mouse brains (~8-fold relative to 5XFAD controls).Back to article page