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Figure 10 | Molecular Brain

Figure 10

From: Characterization of Aldh2 -/- mice as an age-related model of cognitive impairment and Alzheimer’s disease

Figure 10

Increased nicastrin and decreased neprilysin expression in hippocampi from 12 month Aldh2 -/- mice. Immunoblot analysis of hippocampal homogenates (30 μg protein) from 12 month old wildtype and Aldh2 -/- mice probed for nicastrin (A) and neprilysin (B). Immunoreactive bands were quantitated by densitometry. Data are presented as the mean ± SD (n = 4 mice) and were analyzed by Student’s t-test for unpaired data. ***, significant difference from wildtype (p < 0.001).

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