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Figure 2 | Molecular Brain

Figure 2

From: Characterization of Aldh2 -/- mice as an age-related model of cognitive impairment and Alzheimer’s disease

Figure 2

Age-dependent, progressive decline in Y-maze task performance in Aldh2 -/- mice. The spontaneous alternation rate in the Y-maze task was assessed in male and female mice once per month beginning at three months of age. Data are presented as the mean ± SD (wildtype n = 18, Aldh2 -/- n = 17) and were analyzed by two-way ANOVA with a Bonferroni post-hoc test. *, significant difference from wildtype as indicated (*p < 0.05, **, p < 0.01, ***p < 0.001); ψψψ, significant difference from 3.5-4 month old Aldh2 -/- mice (p < 0.001).

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