TY - JOUR AU - Mu, Li AU - Wang, Jun AU - Cao, Bing AU - Jelfs, Beth AU - Chan, Rosa H. M. AU - Xu, Xiaoxiang AU - Hasan, Mahadi AU - Zhang, Xu AU - Li, Ying PY - 2015 DA - 2015/05/23 TI - Impairment of cognitive function by chemotherapy: association with the disruption of phase-locking and synchronization in anterior cingulate cortex JO - Molecular Brain SP - 32 VL - 8 IS - 1 AB - Patients following prolonged cancer chemotherapy are at high risk of emotional and cognitive deficits. Research indicates that the brain neuronal temporal coding and synaptic long-term potentiation (LTP) are critical in memory and perception. We studied the effects of cisplatin on induction of LTP in the basolateral amygdala (BLA)-anterior cingulate cortex (ACC) pathway, characterized the coordination of spike timing with local theta oscillation, and identified synchrony in the BLA-ACC network integrity. SN - 1756-6606 UR - https://doi.org/10.1186/s13041-015-0125-y DO - 10.1186/s13041-015-0125-y ID - Mu2015 ER -