Fig. 4

Long-term potentiation (LTP)-like plasticity in the basolateral amygdala (BLA)-ACC synapse was impaired in cisplatin-treated rats. a Representative ACC evoked local field potential (LFP) responses to different-intensity BLA stimuli (200, 400 and 800 μA) in both control and cisplatin rats. b Averaged input/output (I/O) curves of BLA-ACC evoked LFP showed no significant alteration between control and cisplatin-treated rats. c Examples of LFP responses in the ACC to BLA stimuli before (pre-) and 40 min after (post-) theta burst stimulation (TBS) in control and cisplatin-treated rats. d LTP was reliably induced in control rats (n = 5). But in cisplatin-treated rats, the LTP induction was impaired when tested with a stimulate intensity that evoked about 50 % of the maximum LFP amplitude (n = 6). Results are expressed as mean ± SEM