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Fig. 11 | Molecular Brain

Fig. 11

From: Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

Fig. 11

Arf6 expression spreads through the Hippocampus with progression of Alzheimer’s disease. Hippocampal sections from Alzheimer’s disease and Control subjects were stained with an antibody to Arf6. In low power images images (Aperio Slide scanner), Arf6 can be seen darkly staining CA1-CA4 pyramidal cells in AD brain (a) but only CA1 and CA2 in Control sample (b) Hippocampal Granule cells (gran) are only lightly stained. Scale Bar 1000 μm. Panel c shows high power (40X) images of representative pyramidal cells from each hippocampal region (scale bar 50 μm)

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Molecular Brain

ISSN: 1756-6606