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Fig. 2 | Molecular Brain

Fig. 2

From: Novel function of PIWIL1 in neuronal polarization and migration via regulation of microtubule-associated proteins

Fig. 2

PIWIL1 is required for the multipolar–bipolar transition of postmitotic neurons. a, d Morphology of labeled neurons in different cortical regions 3 or 5 days post-IUE with siRNA 1. b, e Traces of labeled neurons 3 or 5 days after IUE respectively. c, f Percentage of bipolar cells (white arrows) in different cortical regions. Data are from at least 3 independent IUE experiments. g Typical morphology of labeled mouse neurons in the IZ 3 days after IUE with RNAi 2 or RNAi 2 plus HIWI compared with individual control plasmid. h Percentage of bipolar cells at the IZ of electroporated mouse cortex. Scale bar, 30 μm. Error bar, SEM, **P < 0.01, ***P < 0.001 (Student’s t-test)

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