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Fig. 3 | Molecular Brain

Fig. 3

From: Novel function of PIWIL1 in neuronal polarization and migration via regulation of microtubule-associated proteins

Fig. 3

PIWIL1 knockdown impairs polarization of cortical neurons ex vivo. a Diagram of the ex vivo assay. b, c Average numbers of primary neurites of electroporated cells. d Immunostaining: cultured neurons with PIWIL1 knockdown exhibited multipolar morphology and lower levels of Tau but not Tuj1. e Average neurites’ fluorescence intensity of Tau in GFP+ neurons. Scale bar, 20 μm. Error bar, SEM, *P < 0.05, ***P < 0.001 (Student’s t-test)

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Molecular Brain

ISSN: 1756-6606