Fig. 6

The figure shows different parameters of mechanical stimulus-evoked excitation in sham and SNI mice, 15 and 30 days (dd) after the induction of SNI. “a” shows schematic illustration of mechanical stimulation applied to the hind paw (contralateral to the mPFC). “b”, “c” and “d” show the mean ± standard error of the spontaneous activity, the duration and the onset of excitation in the different groups of mice (n = 10). “e” shows relative EAP slopes.* indicates statistically significant difference versus sham mice. ° indicates significant difference versus SNI 15 days mice. P < 0.05 has been considered as value of significance. The double symbol indicates P < 0.01 and the triple symbol indicates P < 0.001. “f” shows representative spike-waveform of mPFC (+) neurons recorded in sham, SNI 15 days and SNI 30 days mice