Fig. 1
From: Persistent pain alters AMPA receptor subunit levels in the nucleus accumbens
Paw incision (PI) leads to short-term pain and depression-like behaviors. a PI-treated rats developed mechanical allodynia up to two days after surgery, compared with control rats that underwent isofluorane treatment without surgery. Two-way ANOVA with Bonferroni post-test, n = 6, ****p < 0.0001. On day 7 after PI, there was no statistical difference in the withdrawal threshold between the PI and control groups. b PI decreased sucrose preference on the SPT on day 1 and 2 after the procedure, Two-way ANOVA with Bonferroni post-test, n = 10, *P < 0.05. c PI caused no changes in total fluid consumption on the SPT 1 day after surgery. Student’s t-test, n = 10, p > 0.05. d PI caused a decrease trend of sucrose consumption on the SPT 1 day after surgery. Student’s t-test, n = 10, p > 0.05. e PI caused an increased trend of water consumption on the SPT 1 day after surgery. Student’s t-test, n = 10, p > 0.05. Error bars show mean and SEM