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Fig. 2 | Molecular Brain

Fig. 2

From: Persistent pain alters AMPA receptor subunit levels in the nucleus accumbens

Fig. 2

Complete Freund’s Adjuvant (CFA) causes persistent inflammatory pain and depression-like behaviors. a Rats developed mechanical allodynia after CFA injection, compared with control (saline) injection. Two-way ANOVA with Bonferroni post-test, n = 6–9, **p < 0.01, ****p < 0.0001. b Rats developed decreased sucrose preference on the SPT on day 1, 2 and 7 after CFA injection. Two-way ANOVA with Bonferroni post-test, n = 6–11, *p < 0.05, **p < 0.01. c CFA caused no changes in total fluid consumption on the SPT 7 days after injection. Student’s t-test, n = 10–11, p > 0.05. d CFA caused a decreased trend of sucrose consumption on the SPT 7 days after injection. Student’s t-test, n = 10–11, p > 0.05. e CFA caused increased water consumption on the SPT 7 days after injection. Student’s t-test, n = 10-11, *p < 0.05. Error bars show mean and SEM

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