Fig. 3
From: Persistent pain alters AMPA receptor subunit levels in the nucleus accumbens
Spared nerve injury (SNI) causes persistent neuropathic pain and depression-like behaviors. a SNI-operated rats developed persistent mechanical allodynia after surgery, compared with sham-operated rats. Two-way ANOVA with Bonferroni post-test, n = 4–9, ****p < 0.0001. b SNI-treated rats developed worse sucrose preference than sham-treated rats on postoperative day 7 and 14. Two-way ANOVA with Bonferroni post-test, n = 4–10, *p < 0.05, **p < 0.01. c SNI caused no changes in total fluid consumption on the SPT 7 days after surgery. Student’s t-test, n = 9–10, p > 0.05. d SNI caused decreased sucrose consumption on the SPT 7 days after surgery. Student’s t-test, n = 9–10, *p < 0.05. e SNI caused increased water consumption on the SPT 7 days after surgery. Student’s t-test, n = 9–10, *p < 0.05. Error bars show mean and SEM