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Fig. 6 | Molecular Brain

Fig. 6

From: Persistent pain alters AMPA receptor subunit levels in the nucleus accumbens

Fig. 6

Persistent inflammatory pain causes the formation of GluA2-lacking AMPA receptors in the NAc. a-c Neurons in the NAc from rats that received CFA injection showed decreased EPSCs at depolarized voltages, compared with neurons from rats that received saline treatment. a, b Representative traces; c Normalized cumulative current–voltage relationship. d EPSCs from CFA-treated rats showed increased rectification index. Student’s t test, n = 10-12 neurons from 3 rats, **p < 0.01. e Schematic of the NAc showing EP recording sites in red circles. Recordings were done 7 days after either CFA or saline injection. Error bars show mean and SEM

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