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Table 1 Method of antibody detection and investigated target antigens

From: Gilles de la Tourette syndrome is not linked to contactin-associated protein receptor 2 antibodies

Cell based (HEK293)    Tissue section   Immunblot
Surface antigen Site (spezies)
  Positive Total   Staining
CASPR 0 51 hippocamcus (rat) IIF GAD65 Amphyphysin
Ampa 1 0 51 cerebellum (rat) IIF Zic4 CV2 (CRMP5)
Ampa 2 0 51 cerebellum (monkey) DAB Tr (DNER) Ri
LGI 1 0 51    SOX1 Yo
GABAB 1/2 0 51    Ma 2 HuD
NMDAR 0 51    Ma 1  
    (n = 51) (n = 7)
  1. Transfected cells ectopically expressing (CASPR2), N-methyl-D-aspartic acid receptor (NMDAR), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), Leucin-rich glioma inactivated protein (LGI1), or gamma-aminobutyric acid receptor (GABAB1/B2). Intracellular antigens: Glutamate-Decarboxylase (GAD), Zinc-Finger-Protein4 (Zic4), Delta/Notch-like Epidermal Growth Factor-Related Receptor (DNER), Glia-Nuclear (SOX1), Paraneoplastic Antigen1 (Ma1), Paraneoplastic Antigen2 (Ma2), Amphiphysin, Collapsin-Response Mediator -Protein 5 (CRMP5/CV2), Purkinje cell Antigen1 (Yo), Neuronal-Nuclear Antigen1 (HuD), Neuronal-Nuclear Antigen2 (Ri)