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Table 1 Method of antibody detection and investigated target antigens

From: Gilles de la Tourette syndrome is not linked to contactin-associated protein receptor 2 antibodies

Cell based (HEK293)

  

Tissue section

 

Immunblot

Surface antigen

Site (spezies)

 

Positive

Total

 

Staining

CASPR

0

51

hippocamcus (rat)

IIF

GAD65

Amphyphysin

Ampa 1

0

51

cerebellum (rat)

IIF

Zic4

CV2 (CRMP5)

Ampa 2

0

51

cerebellum (monkey)

DAB

Tr (DNER)

Ri

LGI 1

0

51

  

SOX1

Yo

GABAB 1/2

0

51

  

Ma 2

HuD

NMDAR

0

51

  

Ma 1

 
   

(n = 51)

(n = 7)

  1. Transfected cells ectopically expressing (CASPR2), N-methyl-D-aspartic acid receptor (NMDAR), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), Leucin-rich glioma inactivated protein (LGI1), or gamma-aminobutyric acid receptor (GABAB1/B2). Intracellular antigens: Glutamate-Decarboxylase (GAD), Zinc-Finger-Protein4 (Zic4), Delta/Notch-like Epidermal Growth Factor-Related Receptor (DNER), Glia-Nuclear (SOX1), Paraneoplastic Antigen1 (Ma1), Paraneoplastic Antigen2 (Ma2), Amphiphysin, Collapsin-Response Mediator -Protein 5 (CRMP5/CV2), Purkinje cell Antigen1 (Yo), Neuronal-Nuclear Antigen1 (HuD), Neuronal-Nuclear Antigen2 (Ri)
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Molecular Brain

ISSN: 1756-6606