Fig. 2
Expression profile of mGlu receptors in CA1 and CA3 regions at times preceding neuronal death. Quantitative PCR analysis of (a) mGlu2, (b) mGlu3, (c) mGlu1 and (d) mGlu5 receptors (mGluR1, -2, -3, and -5) at 12 and 24 h after reperfusion. mRNA values, expressed as copy number, were normalized to β-actin and are means ± S.E.M. of 3-5 rats per group; One-way ANOVA + Fisher's LSD: In (a) mGluR2 at 12 h post ischemia: F(3,15) = 7.6, p < 0.05; mGluR2 at 24 h post ischemia: F(3,15) = 7.1, p < 0.05; in (b) mGluR3 at 24 h: F(3,14) = 2.6, p < 0.05; in (c) mGluR1 at 24 h post ischemia: F(3,14) = 9.2, p < 0.05. Post-hoc analysis: p < 0.05 vs. the respective values obtained in sham operated rats (*); or vs. the respective values obtained in the CA1 region (#)